Anti-Diabetic Drugs
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چکیده
Diabetes mellitus affects up to 6% of the UK population, although it is estimated that around half of these individuals remain undiagnosed. It occurs equally in both sexes but varies with age and race. The ethnic group at highest risk is the Pima Indians in North America with a 50% prevalence of diabetes. Other high-risk groups include the Afro-Caribbean and Asian populations, who are at four times the risk for developing diabetes than Caucasians.
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Evaluation of Serum Vaspin and Chemerin Levels in Type 2 Diabetic and Treated with Anti Diabetic Drugs Metformin and Acarbose in Rats
Background & Objective: The serum levels of adipose tissue hormons, Vaspin and Chemerin, alter in some disorder conditions such as diabetes. The aim of this study is to investigate the effect of two anti-diabetic drugs (Metformin and Acarbose) and their combination on serum concentration of Vaspin and Chemerin in type 2 diabetic rats. Materials & Methods: 30 male, wistar rats are randomly d...
متن کاملAccess to Anti-Diabetic Medicines among Patients Attending Tertiary Health Facilities in Oyo State, Nigeria
Objective: The management of Diabetes Mellitus (DM) is longterm and can be expensive. This study aimed to describe access to anti-diabetic medicines among patients in tertiary health care facilities in Oyo State, Nigeria. Materials and Methods: This was a hospital-based crosssectional study. The study sites were the University College Hospital (UCH), Ibadan, and Ladoke Akintola University Teach...
متن کاملEvaluation of the Effect of Perindopril and its Combination with Oral Anti-Diabetic Drugs on Blood Sugar Levels in Diabetic Wistar Rats
It is well known scientifically that ACE (Angiotensin converting enzyme) inhibitors prevent the development and progression of incipient or established nephropathy and delay the progression of diabetic retinopathy hence these drugs are routinely prescribed with the oral anti-diabetic drugs in these conditions. The actual scenario of impact of ACE inhibitors on blood glucose is still controversi...
متن کاملCynara scolymus L. in Treatment of Hypercholesterolemic Type 2 Diabetic Patients: a Randomized Double-Blind Placebo-Controlled Clinical Trial
Background: Type 2 diabetes mellitus with hyperlipidemia is a common disease. Conventional anti-hyperglycemic and anti-hyperlipidemic drugs have limited efficacies and important side effects, so that alternative agents are needed. Previous studies suggest that fiber-free artichoke (Cynara scolymus L.) leaf extract may have anti-hyperglycemic and anti-hypercholesterolemic effects in hypercholest...
متن کاملEffects of Enalapril on Blood Glucose Level and Interaction with the Oral Anti-diabetic Drugs in Alloxan-induced Diabetic Rats
Aim: To evaluate the effect of Enalapril on blood glucose level in normal rats and interaction with the oral anti-diabetic drugs in Alloxan-induced diabetic rats. Method: The rats were classified into nine groups (n = 6).The Group I –II were normal and Group III –IX were diabetic. The experimental diabetes in rats was induced by intra-peritoneal injection of Alloxan monohydrate (135 mg/kg body ...
متن کاملBioavailability studies of selected oral anti-diabetic drugs in human volunteers - A review
The intestinal absorption of oral-anti diabetic drugs in type-II Diabetes mellitus is altered when concomitantly administered with other drugs like, antacids, antinuclear drugs, antibiotics and others. Drug therapy becomes more complex as many individuals are on multiple drug therapy and administer many drugs during same period of time. An increasing number of drug related problems caused by dr...
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